Yes& the late Mr. Darcy bequeathed me the next presentation of the best living in his gift. 怎么会不是!老达西先生遗嘱上说明,牧师职位一有了最好的空缺就给我。
Sex with management can be a huge ego boost, not to mention the chance to max out the company credit card after "working late" on that all-important presentation. 与管理者发生性关系,可以使你获得巨大的个人提升,更不用说在所有重要场合“工作到很晚”之后,有机会尽情地透支公司信用卡。
Up to20% develop distant metastasis, which can occur as late as20 years after original presentation. Therefore, long-term follow-up is necessary. 超过20%的会出现远端转移,可以发生在发病20年后,因此长期的随诊是必须的。
Because most patients have not special clinical situation and most patients are late stage at first presentation, its local infiltration and remote metastasis lead to difficult radical operation. Survival rate is low and prognosis is poor after operation. 因胆管癌早期无特异性临床表现,发现症状时大部分已为晚期,其局部浸润和远隔转移导致手术很难达到根治目的,患者术后生存率低,预后差。
The disease course of the AD-EDMD is generally slow, but we can observe milder phenotype characterized by late onset and a mild degree of weakness and contractures or more severe phenotype with early presentation and a rapidly progressive course in few cases. 常染色体显性型患者病程一般发展缓慢,但我们也观察到发病较晚,仅有轻度肌肉无力和挛缩的轻型患者以及少数发病早,病情进展迅速的严重型患者。
Conclusions Hypertrophic cardiomyopathy in Chinese patients is characterized by late onset of presentation, and the ratio of sex and clinical findings are different from those of other areas. 结论华北地区肥厚型心肌病患者发病时间晚,性别比例以及临床表现不同于其它地区。